Acido Mefenamico

Acido Mefenamic: An In-Depth Guide

What is Acido Mefenamic?

Acido Mefenamic, also known by its brand name Ponstan, is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, fever, and inflammation. It belongs to the fenamate class of NSAIDs, which includes other drugs such as meclofenamate and flufenamic acid.

Mechanism of Action

Acido Mefenamic works by inhibiting the enzyme cyclooxygenase (COX), which is responsible for the production of prostaglandins. Prostaglandins are hormone-like substances that play a role in inflammation, pain, and fever. By blocking COX, Acido Mefenamic reduces the production of prostaglandins, thereby reducing inflammation, pain, and fever.

Indications

Acido Mefenamic is indicated for the treatment of a variety of pain conditions, including:

• Headaches
• Toothaches
• Menstrual cramps
• Muscle pain
• Back pain
• Osteoarthritis
• Rheumatoid arthritis

Dosage and Administration

Acido Mefenamic is available in tablet and capsule form. The usual dosage for adults is 500 mg every 6 to 8 hours as needed for pain or inflammation. The maximum daily dose is 1,500 mg.

Side Effects

Like all medications, Acido Mefenamic can cause side effects. The most common side effects include:

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Constipation
• Dizziness
• Headache
• Drowsiness

More serious side effects can occur, but are less common. These include:

• Gastrointestinal bleeding
• Liver damage
• Kidney damage
• Anaphylaxis
• Stevens-Johnson syndrome
• Toxic epidermal necrolysis

Drug Interactions

Acido Mefenamic can interact with other medications, including:

• Anticoagulants (blood thinners)
• Antiplatelet drugs (blood thinners)
• Lithium
• Methotrexate
• Probenecid
• Valproic acid

It is important to tell your doctor about all medications you are taking, including over-the-counter medications, vitamins, and herbal supplements.

Contraindications

Acido Mefenamic is contraindicated in patients with:

• A history of gastrointestinal bleeding or ulcer
• Severe liver disease
• Severe kidney disease
• Asthma
• Urticaria (hives)
• Angioedema

Precautions

Acido Mefenamic should be used with caution in patients with:

• A history of heart disease
• A history of stroke
• A history of high blood pressure
• A history of diabetes
• A history of kidney disease
• A history of liver disease
• A history of seizures
• A history of mental illness

Acido Mefenamic is also contraindicated in patients who are pregnant or breastfeeding.

Conclusion

Acido Mefenamic is a safe and effective medication for the treatment of a variety of pain conditions. However, it is important to be aware of the potential side effects and drug interactions before taking this medication.

If you have any questions or concerns about Acido Mefenamic, please talk to your doctor.